So, how is a thyroid problem diagnosed?1.Anultrasoundscanmayberequestedtomeasuretheshapeofthethyroidandtolookfornodulesor cysts within the gland. 2.Fineneedleaspirationcytology(FNAC).Thisisanextremelyvaluabletestfordiagnosingthyroidlumps. Asmallsampleofcellsorfluidisremovedfromthethyroidglandbypassinganeedlethroughthenoduleor cystinthegland.Theaspirateisthenexaminedunderthemicroscopeandthetypeofcellsmakingupthe swellingcanbeseen.Thetestisusually80-90percentaccurate.Histology(Studyofthecellsmakingupthe sweling)ofthemassinquestionisimportanttodifferentiateacancerousandnon-canceroustype,andfurther tothat,whichparticularsubtypeofcells.Thisinturnsmakesabigdifferenceinthesubsequenttreatmentof the mass.
Alternatively, FNAC can be more accurately performed under ultrasound guidance, called ultrasound-guided FNAC. It is more superior for deep-seated masses as the ultrasound allow a real-time precise targeting of the needle into the lesion in question (analogy is a soldier wearing a night-vision infra-red goggle in pitch-black darkness shooting at a target !) Other than thyroids, this technique can also be applied to other head and neck masses, as in here.The advantages of ultrasonography is that it is rapid, inexpensive, versatile, no ionizing radiation (eg. CT scan, X ray) is applied, does not require injection of contrast medium and can be easily repeated when necessaryUltrasound guided fine needle aspiration cytology (FNAC) is a safe diagnostic procedure in which any structure visualized can be reached quickly and precisely by a fine needle in any desired plane with constant visualization of the needle tip during insertion.3.Endoscopicexaminationofthevocalcordstoexcludepotentialinvolvementofthenerve (recurrentlaryngealnerveRLN)supplyingthevocalcordspre-andpost-surgery.Thiscanbedonein the outpatient clinic after applying some local anaesthetic nasal spray.Asathyroidcancermayinfiltrateintothenervesupplyingthevocalcordmuscles,similarlythethyroid surgeryitselfmaypotentiallyaffectthefunctionofthenerve,itisvitaltoknowthestatusofthevoice box(vocalcords)beforeandafterthesurgery.Anyvocalcordweaknesscanaffectthevoiceand swallowing function..
Colloid NodulesThese are benign nodules made up of thyroid tissue that have become enlarged. They can be single or multiple and can sometimes become very large. Surgery becomes necessary if the nodule becomes large and causes compressive symptoms or if they cause cosmetic deformity.Non-Cancerous TumoursThesetumours(generally'adenoma')arecausedbyanabnormalgrowthofthyroidfolliclecells.Theyhavenocapacitytospreadorcause destructionoftissuebuttheycannotbedifferentiatedfromoneofthetypesofthyroidcanceronFNAC(pleaseseenextcolumn).Surgeryisusually recommended for diagnosis. THYROID CANCERThemostcommonthyroidcancersaredifferentiatedthyroidcancersnamedeitherpapillaryorfollicularcancer.Thesemakeupmorethan90%of thyroidcancerandtheyveryrarelycausedeath.Theydohavethepotentialtospreadtolymphnodesintheneckandtootherpartsofthebody such as the lungs but even if they do, these tumours are still treatable. Surgery is necessary in most cases.So what are the complications?Goitres,especiallyMNG,canbecomeverylargeandcausepressureonthewindpipe(trachea)andswallowingtube(oesophagus).Thiscanresult in shortness of breath, voice change, cough, increased pressure sensation in the neck and sometimes difficulty swallowing.Surgerytoremovethethyroidglandisusuallynecessarytotreatlargegoitresthatarecausingsymptoms.Surgeryisalsonecessarywherethereis a suspicion of thyroid cancer in an enlarged thyroid gland and where the swelling is causing cosmetic deformity.
THYROID - PART 2 (HORMONAL IMBALANCE)
What can go wrong with it ?However,lumpsormassescanariseinthethyroidcausingdifferentthyroiddiseases. Avisible enlargementofthethyroidglandiscalledGoitre.Theentireglandmaybeinvolvedorthere maybesingleormultiplenodulesorlumps.Thyroidmassescanalsobeassociatedwith hormonalimbalance.Patientswithoveractiveorunder-activethyroidglandscanhavegoitre but most goitres produce a normal amount of thyroxine.AnoveractivethyroidglandwouldproducetoomuchthyroxinecausinghyperthyroidismThe symptomsofthisconditionincludetremor,heatintolerance,irritability,increasedenergy,poor sleep, weight loss and frequently, bulging eyes. Patients generally have a high metabolic rate.Too little thyroxine from an under-active gland causes an illness with a low metabolic rate called hypothyroidism.Thisconditioncausestiredness,weightgain,swellingandslownessofspeech and thinking.Single NoduleAsingleswellingorlump(nodule)inthethyroidglandisaspecialformofgoitre.Themajority (90%)ofthenodulesarenotcancerousbuteithersimpleswellingsoffluid(cysts)orbenign growths of thyroid tissue with no tendency to spread or invade structures.Theremaining10%areusuallyaverylow-gradeformofcancer,whichisalmostalways completelycurable.Thereareaverysmallnumberofnodulesthatturnouttobeamore aggressive form of thyroid cancer, these occur in special situations and are very rare.Multinodular Goitre (MNG)Frequentlythelumpsarenotsinglebutmultipleandpartofaninnocent,non-cancerous conditioncalledMNG,whichjustmeansthatseveralswellingsarepresent.Occasionallythey can be later found to harbour cancer cells !CystCysts(fluidcollections)inthethyroidarecommon.Frequentlytheyarepresentwithoutthe patient noticing but sometimes they can enlarge so that they can be felt.
SO YOU THINK YOU HAVE A THYROID SWELLING ?
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Talks about HYPERTHYROIDISM on 20/12/16(for educational purposes, in Mandarin, copyright ntv7)
Talks about NECK SWELLING on 2/1/15(for educational purposes, in BM, copyright TV9)
Talks about THYROID on 6/12/16(for educational purposes, in BM, copyright TV3)
THYROID disorders
What is a thyroid gland ?The thyroid gland is a small organ in the midline of the neck, just below the Adam's apple (larynx).It is easy to recognize a thyroid swelling- it moves up on swallowing !Thefunctionofthethyroidglandistomakeahormonecalled'thyroxine'.Anormalamountof thyroxineisrequiredfornormalphysicalandmentaldevelopment.Inadults,thyroxinekeepscells and tissues working at just the right metabolic rate.
RELATED LINKS
Head & Neck Swellings
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Ultrasound-guided biopsy
Ear, Nose and Throat (ENT), Thyroid, Head and Neck
Alternatively, FNAC can be more accurately performed under ultrasound guidance, called ultrasound-guided FNAC. It is more superior for deep-seated masses as the ultrasound allow a real-time precise targeting of the needle into the lesion in question (analogy is a soldier wearing a night-vision infra-red goggle in pitch-black darkness shooting at a target !) Other than thyroids, this technique can also be applied to other head and neck masses, as in here.The advantages of ultrasonography is that it is rapid, inexpensive, versatile, no ionizing radiation (eg. CT scan, X ray) is applied, does not require injection of contrast medium and can be easily repeated when necessaryUltrasound guided fine needle aspiration cytology (FNAC) is a safe diagnostic procedure in which any structure visualized can be reached quickly and precisely by a fine needle in any desired plane with constant visualization of the needle tip during insertion.3.Endoscopicexaminationofthevocalcordstoexclude potentialinvolvementofthenerve(recurrentlaryngealnerve RLN)supplyingthevocalcordspre-andpost-surgery.This canbedoneintheoutpatientclinicafterapplyingsomelocal anaesthetic nasal spray.Asathyroidcancermayinfiltrateintothenervesupplyingthe vocalcordmuscles,similarlythethyroidsurgeryitselfmay potentiallyaffectthefunctionofthenerve,itisvitaltoknow thestatusofthevoicebox(vocalcords)beforeandafterthe surgery.Anyvocalcordweaknesscanaffectthevoiceand swallowing function..
So, how is a thyroid problem diagnosed?1.Anultrasoundscanmayberequestedtomeasurethe shapeofthethyroidandtolookfornodulesorcystswithinthe gland. 2.Fineneedleaspirationcytology(FNAC).Thisisan extremelyvaluabletestfordiagnosingthyroidlumps.Asmall sampleofcellsorfluidisremovedfromthethyroidglandby passinganeedlethroughthenoduleorcystinthegland.The aspirateisthenexaminedunderthemicroscopeandthetypeof cellsmakinguptheswellingcanbeseen. Thetestisusually80-90percentaccurate.Histology(Studyofthecellsmakingupthe sweling)ofthemassinquestionisimportanttodifferentiatea cancerousandnon-canceroustype,andfurthertothat,whichparticularsubtypeofcells.Thisinturnsmakesabigdifference in the subsequent treatment of the mass.
What can go wrong with it ?However,lumpsormassescanariseinthethyroidcausing differentthyroiddiseases.Avisibleenlargementofthethyroid glandiscalledGoitre.Theentireglandmaybeinvolvedorthere maybesingleormultiplenodulesorlumps. Thyroidmassescan alsobeassociatedwithhormonalimbalance.Patientswith overactiveorunder-activethyroidglandscanhavegoitrebut most goitres produce a normal amount of thyroxine.Anoveractivethyroidglandwouldproducetoomuchthyroxine causinghyperthyroidismThesymptomsofthisconditioninclude tremor,heatintolerance,irritability,increasedenergy,poorsleep, weightlossandfrequently,bulgingeyes.Patientsgenerally have a high metabolic rate.Toolittlethyroxinefromanunder-activeglandcausesanillness withalowmetabolicratecalledhypothyroidism.Thiscondition causestiredness,weightgain,swellingandslownessofspeech and thinking.Single NoduleAsingleswellingorlump(nodule)inthethyroidglandisa specialformofgoitre.Themajority(90%)ofthenodulesarenot cancerousbuteithersimpleswellingsoffluid(cysts)orbenign growthsofthyroidtissuewithnotendencytospreadorinvade structures.Theremaining10%areusuallyaverylow-gradeformofcancer, whichisalmostalwayscompletelycurable.Thereareavery smallnumberofnodulesthatturnouttobeamoreaggressive formofthyroidcancer,theseoccurinspecialsituationsandare very rare.Multinodular Goitre (MNG)Frequentlythelumpsarenotsinglebutmultipleandpartofan innocent,non-cancerousconditioncalledMNG,whichjust meansthatseveralswellingsarepresent.Occasionallytheycan be later found to harbour cancer cells !CystCysts(fluidcollections)inthethyroidarecommon.Frequently theyarepresentwithoutthepatientnoticingbutsometimesthey can enlarge so that they can be felt.
Colloid NodulesThese are benign nodules made up of thyroid tissue that have become enlarged. They can be single or multiple and can sometimes become very large. Surgery becomes necessary if the nodule becomes large and causes compressive symptoms or if they cause cosmetic deformity.Non-Cancerous TumoursThesetumours(generally'adenoma')arecausedbyan abnormalgrowthofthyroidfolliclecells.Theyhavenocapacity tospreadorcausedestructionoftissuebuttheycannotbe differentiatedfromoneofthetypesofthyroidcanceronFNAC (pleaseseenextcolumn).Surgeryisusuallyrecommendedfor diagnosis. THYROID CANCERThemostcommonthyroidcancersaredifferentiatedthyroid cancersnamedeitherpapillaryorfollicularcancer. Thesemake upmorethan90%ofthyroidcancerandtheyveryrarelycause death.Theydohavethepotentialtospreadtolymphnodesin theneckandtootherpartsofthebodysuchasthelungsbut eveniftheydo,thesetumoursarestilltreatable.Surgeryis necessary in most cases.So what are the complications?Goitres,especiallyMNG,canbecomeverylargeandcause pressureonthewindpipe(trachea)andswallowingtube (oesophagus).Thiscanresultinshortnessofbreath,voice change,cough,increasedpressuresensationintheneckand sometimes difficulty swallowing.Surgerytoremovethethyroidglandisusuallynecessaryto treatlargegoitresthatarecausingsymptoms.Surgeryisalso necessarywherethereisasuspicionofthyroidcancerinan enlargedthyroidglandandwheretheswellingiscausing cosmetic deformity.
THYROID - PART 2 (HORMONAL IMBALANCE)
What is a thyroid gland ?Thethyroidglandisasmallorganinthemidlineoftheneck, just below the Adam's apple (larynx).Itiseasytorecognizeathyroidswelling-itmovesupon swallowing !Thefunctionofthethyroidglandistomakeahormonecalled 'thyroxine'. Anormalamountofthyroxineisrequiredfornormal physicalandmentaldevelopment.Inadults,thyroxinekeeps cells and tissues working at just the right metabolic rate.
SO YOU THINK YOU HAVE A THYROID SWELLING ?
Bahasa/语文 :
Talks about HYPERTHYROIDISM on 20/12/16(for educational purposes, in Mandarin, copyright ntv7)
Talks about NECK SWELLING on 2/1/15(for educational purposes, in BM, copyright TV9)
Talks about THYROID on 6/12/16(for educational purposes, in BM, copyright TV3)
Ear, Nose and Throat (ENT), Thyroid, Head and Neck